Glossary

Diabetes (mellitus)
Inability to metabolise glucose due to lack of insulin production (type1) or lack of insulin efficacy or availability (type2).

Ferritin
A complex protein formed in the intestine, containing about 23% iron, the amount found in serum is directly related to iron storage in the body. Increased ferritin levels may indicate iron loading and conditions such as haemochromatosis, certain types of anaemia etc.

Folic acid
Part of the B complex of vitamins and needed for normal function of red and white blood cells.

Haemochromatsois
Genetic metabolic disorder in which excessive iron may accumulate in the liver, pancreas, heart, brain, and skin resulting in liver disease, diabetes mellitus, heart attack, depression, impotence, and a bronze or ashen grey – green skin colour. It is a condition in which an excess of iron is absorbed from the diet and stored in the body.

Haemoglobin
The iron containing pigment of red blood cells that carries oxygen from the lungs to the tissues.

Haemosiderosis
A condition marked by excessive iron in the tissues especially in the liver and spleen.

Hepatitis
Inflammatory liver condition.

Homozygous
If an individual has the C282Y mutation on both chromosomes that person is referred to as being homozygous for C282Y . In Ireland it is estimated that 1 in 80 people in the general population are homozygous for C282Y. An individual can also have the H63D mutation on both chromosomes and this person would be homozygous for H63D

Hyperthyroidism
Over activity of the thyroid, an endocrine gland that regulates all body functions.

Hypothyroidism
an underactive thyroid gland which results in decreased metabolic rate.

Iron overload
Too much iron in the body, excess accumulates in vital organs resulting in disease.

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